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286 Weighted blankets are sometimes promoted for their calming effect, and clinical evidence indicates they may be especially helpful in adults and children with attention deficit hyperactivity disorder (ADHD) and/or autism spectrum disorder
Visceral adiposity contributes to chronic low-grade inflammation through macrophage activation, altered T-cell responses, and adipokine imbalance ( Beyond obesity, insulin resistance and hyperinsulinemia appear to play an active role in sustaining inflammatory arthritis rather than representing mere epiphenomena of chronic inflammation
Patients are encouraged to follow regulatory progress through official MHRA and NHS England communications, and to identify eligible trials via the NIHR Be Part of Research portal (bepartofresearch.nihr.ac.uk), rather than relying on anecdotal or commercial sources
